Sunday, September 25, 2011

Clinical trials claimed almost 1,600 lives (officially) in India in just 3 yrs


The disturbing article published in Indian Express on 25th September 2011. It says, “nearly 1,600 people died during clinical trials of drugs conducted by various multinational pharmaceutical companies in the 2008-10 period but the compensation was paid only in 22 cases, according to the Directorate General of Health Services (DGHS)”. The cost of 22 lives of those who volunteered in such clinical trials is just Rs 53.33 lakh ($ 112,000). Most of the volunteers hardly have any idea about the risks. They also do not get many of the safeguards, enforced in any developed country, to protect their health, mainly after trials. According to the RTI reply, the number of registered clinical trials in the country from 2007 to 2010 stood at 1,502.


While outsourcing drug trials save significant money for the pharmaceutical companies, the cost of human lives and suffering for both the trial participants in developing countries and drug users in developed countries is likely to be horrendous. Many have questioned how appropriate and ethical it is to test drugs intended for the American and European markets in developing countries. Duke University`s recent report, Ethical and Scientific Implications of the Globalization of Clinical Research, labeled clinical trials in developing countries as scientifically questionable and morally inappropriate. The study noted that genetic and other population differences could render results that did not apply to the target population. The report also raised concerns over the role money might play in recruiting poor volunteers. As recently as 1990, only 271 trials of drugs intended for American use were being conducted in foreign countries. By 2008, the number had risen to 6,485. According to a National Institutes of Health (NIH) database 58,788 such foreign trials have been conducted in 173 countries outside the United States since 2000. In 2008 alone, 80 percent of the applications submitted to the FDA for new drugs contained data from foreign clinical trials.



India is increasingly being used not only by big pharma and other biotech companies from abroad, but also by many highly dubious Indian companies in areas like clinical trials, testing (and production) of transgenic crop varieties, “research” on harmful chemicals etc. Another such industry is asbestos, widely used in India. Most of the countries in the world had banned asbestos. India is yet to ban its use, production and import despite many reports to show its damaging impact on environmental and public health. One such report says India is on the cusp of a devastating asbestos cancer epidemic. There are many such industries operating successfully and with impunity in India.



Leave alone the smaller players, who operate under the radar, even the big Indian companies are alleged to having increasing involvement in such practices. In March 2004, the Supreme Court of India hauled up two top biotech companies in India, the Hyderabad-based Shanta Biotech and Bangalore-based Biocon India for "openly conducting illegal clinical trials of new drugs on unsuspecting patients". One can watch this interesting TV documentary to know more about it, how it works.

Our aspiring future scientists and young talents suffer from such practices in the name of research. Academic research also gets affected by the power of such businesses. It has huge long term negative consequences, even in terms of manpower development and quality of research. We need to keep in mind that quality of Indian research is steadily declining since 1996, when systemic data collection started, despite of huge increase in funding and number of new institutes established by both Government and private entities.

It seems that anything is justified in post-1991 India in the name of investment and / or research. It gives our political masters and industry captains the opportunity to advertise their successes, to both Indian and global audience, with a huge cost to the country and its future scientific potential.

Short URL: http://goo.gl/4oSQjk 


Thursday, June 23, 2011

Aranyak


To tell you the truth, I was not impressed at all when I first read Arnayak long time ago, during my school days. We had a small piece from that classic novel in our Bengali textbook. That time it was so boring, monotonous description of nature of our area, Chotonagpur plateau, in India. That description was so common, ordinary to me. I used to see many of the natural wonders described in the book on a daily basis and reading about the same in a book, and that too in a text book, did not excite me. I started reading the novel due to my father's forceful request but left it halfway. It was lying, neglected, in a cupboard with many other old books. I forgot about it.

After a long time my wife bought the book. I started reading it. Now I realized that probably I did the right thing by not reading that classic literature during my teen, when I was too immature to understand nature, human relationship and relationship of nature with human beings. It provoked so many emotions, so many pictures of my lost childhood and more importantly my lost innocence amidst rough, tough nature of chotonagpur plateau. During my childhood I was almost like of some the kids described in that novel.

The novel was written during 1937-1939 by Bibhutibhusan Bandhyodadhya. It was mainly based on his personal experience during 1924-1930, as an estate manager for a landlord Khilat Chandra Ghosh in wild Azamabad - Fulkia – Lobtulia areas of Bihar state. To understand the novel we probably will need to know little more about the author.

Bibhutibhusan was born in 1894 in a village near Kalyani, about 100km away from Kolkata, in British India at his maternal uncle's house, following the tradition that child birth should happen in mother's paternal home or maternal uncle’s home- to save husband and in-laws from the hassles of child birth, to ensure proper care for the new mom and the child and observing so many rituals and restrictions, mainly for new mother, of course. His father, Mahananda Bandyopadhyay, was a sanskrit scholar and a kathak, one who used to tell stories for a living. His home was near Gopalnagar police station in Bongaon, North Twenty Four Parganas. Bhibhutibhusan studied in Bongaon High School, one of the oldest institutions in Brithish India. Incidentally, he also taught at this school at the beginning of his working life. His early days were spent in abject poverty, so typical of an honest scholar and priest, which is still a reality in India. Nevertheless, he fought his way to complete his undergraduate degree in history with distinction, at the Surendranath College, Kolkata. Though he was admitted to the MA and law classes, he could not continue his studies. 

He was married to Gouri Devi. She died in childbirth after only a year of their marriage. Bibhutibhushan again married Rama Chattopadhyay when he was 46. Their only son, Taradas, was born in 1947. Bibhutibhusan died on 1 November 1950, of a heart attack while staying at Ghatshila, in Jharkhand state of Chotonagpur plateau.

Despite of having a childhood in rural India and traveled extensively in that part of India, I did not have much idea about the lives of the common people described in the novel. I had the curiosity but satisfied with watching it from a distance. I neither could gather the courage to proceed further. I started wondering when Satyacharan (the person who narrates the story in the novel) questions himself, “what people want- success or happiness? Why should we succeed if that takes away happiness from us? I know so many people who had succeeded but lost all their happiness. Our consciousness looses its sheen with too much indulgence. We lose the ability to wonder, to become happy. Life becomes so boring, colorless and meaningless. Our minds become too polished to express or extract happiness”. I am not sure if my translation conveys the real meaning of the statement made by Bibhutibusan through Satyacharan. No, I did not have the ability to understand the statement the time I first read Aranyak. Now, I think, I can.

Characters like Jugal Prasad, Raju Pande (Panree), Dhautal Sahu, Nandalal Ojha, Rashbihari Singh, Chutu Singh, Motuk Nath Pandit, Asrafi Tindel, Dhaturia are so real, at least to me, that I could not but recollect so many people that I can assign those characters to. Probably we all know such people around us. 

The descriptions of women in that wild, less forgiving nature indicated Bibhutibhusan’s sensitivity and understanding of human relationship. I really pity those men, those societies who try to strangle, suffocate women and think they can enjoy the charm, the company and even sexuality of women. How stupid they are! They do not know what they are missing. The ease with which tribal princess Bhanumati; Kunta, the daughter of a "baiji" (notch girl) and widow of a Rajput; Manchi- the simple, lively, inquisitive young adult and wife of an old man, are described shows maturity of Bibhutibhusan in man-woman relationship, especially in our highly conservative society, that too in British India.

Bibhutibhusan's attitude towards caste and religion is so evident in many places of the novel. He has no problem to eat and stay with people not only from different caste but also from different religions. The character of Satyacharan was and still is a model of an ideal administrator. It seems that to become a good administrator we need to screen people with both heart and head, not by some rot memorization and coaching based screening test that we use now to make our civil servants. Probably that's why, despite of having the most competitive screening test, Indian civil service is among the most corrupt and ineffective in Asia (1, 2) and "the most stifling" in the world (3). It seems that a head without a heart can only bring darkness to the world.

Many of us, if not majority, still insult people based on social, professional and economic hierarchy. Many of us feel proud thinking they are the descendants of true Aryans and loudly insult people who does not qualify as Aryans - like the tribal king Dobru Panna Birwardi, Jogru Panna or beautiful Bhanumati. We kill so many Dhaturias by not allowing them to learn and express what they love and excel in. We are so blinded by our own distorted interpretation of “education” and “success” that a retired deputy magistrate and his family members never think before they insult Satyacharan, riding a horse in a forest with not so sophisticated dress. Such people hardly care to express their ignorance and stupidity while insulting local, tribal people and their culture. Does our sense of "green" (a catchy phrase for marketing of almost any product these days) have developed in last one century to think before we pollute forests, sea beaches, historical places and many other places of beauty with garbage from their civilized picnic or noisy partying, as we see in almost each and every place in India these days?

Probably such attitude among older (and a small section of current) generation of Bengalis gave rise to mass annoyance, if not anger, against Bengalis in all those places where Bengalis flocked in mass for routine outings  or travel or settled outside Kolkata (which became synonymous to Bengal)- be it within Bengal itself (any person who is not from Kolkata is surely "uncivilized"!) or in North Eastern states, Bihar, UP, MP, Orissa or any other place in India. Many famous Bengali personalities, who used to regularly go to the "west" (west to Bengal- i.e. mainly Bihar, MP, UP and Orissa) for health reason, behaved in the same pathetic way. Majority of them not only exploited and insulted local people and their culture but also practically contributed nothing positive there. Probably it is now payback time for Bengalis in places like North Eastern states, Bihar, Jharkhand, Chattisgarh etc. Later that urban "civilization" spread all across India. What many Bengalis did a century ago, many other Indians learned and continue to do it today. It gave rise to mass frustration and sometimes anger. That is partly responsible for fast spread of extremist movements like Naxals. Some of such naive Indians taste the same medicine when they travel or live abroad. Then they start understanding and then shouting about racial discrimination. They never understood, leave alone analyze, their own behaviors in their own country, against their own people. It is not at all surprising, to me at least, that India is still a highly feudal, hierarchical and racist society.

I am really surprised with the foresightedness of Bibhutibhusan when he questions our model of “development”, when we destroy our century old natural and human wealth for “success” of few people and logic for establishment and spread of slum culture. He did that at the first half of 20th century, when India was much better (relatively speaking) in terms of natural and human beauty. He seemed to be knowing the consequences of spread of third-world style of "development" of towns and metros like Mumbai, Kolkata, Delhi that invariably increase poverty. Have you ever seen filthy open drains, stinking people or crying, malnourished babies running all over in a (economically) poor, remote village anywhere in India, untouched by industrial exploitation? Probably no. Just wait till a factory comes up and see the immediate change!

Have you observed Mumbai, the most prosperous and the financial capital of "shining" India, from the sky? It looks more like a slum city with tarpaulin and blue plastic roof, slums all over with few scattered high rises. Can you imagine a $2 billion house, the costliest in the world, in the midst of sprawling slum anywhere, in any developed country? Probably it is possible only in a third world country like India. Mumbai has more than 60% of its population live in slums (4). Slums have increased dramatically since 1950s, despite of so many developmental programs. A person with 2 million rupees ($ 44,000) annual income, which constitute probably less than 1% of its population, does not dare to buy a decent apartment (leave alone having own house) in a decent locality and settle there in that financial capital. Honest economic activities in those cities are not sufficient to support a family there with decent living. Money from all over India is being accumulated in few metro cities. Yet many consider that as development! It is even more surprising that not many people and our policy makers understand what we are losing while trying to impose “development”, that not so educated Bibhutibhusan understood with his BA in history degree, about a hundred years ago!

Friday, June 17, 2011

Our fight against corruption and Anna Hazare

Probably we all are now aware of the recent uproar against corruption in India. People are angry. If anyone providing them an outlet to vent their frustration they readily grab it and participate in such “mass movements”. Our news hungry 24x7 media is more than happy to oblige anyone with an agenda. Everyone seems to be in favour of such movements. Naturally there is a huge market for it. Even corporate houses sponsoring some of the events. It is really surprising that if everyone is so against corruption, why we have such an extensive and intense corruption in almost every field of life there! The answer may lie in another observation. An office clerk joins Anna Hazare in the evening after taking bribe to protest against A Raja's 2G scam, a student after cheating in exam, a teacher after completing his private tuition evading his  teaching duties in the school, a doctor after prescribing some useless tests to unsuspecting patients and so on.

In reality, Indian society never learned what is democracy, what justice means since long; long before we got independence, long before British occupied the land. It is so contrasting if we think that a king, Gopala, in the Indian state of Bengal was among the first few democratically elected kings in the world (around 750 AD). One wonders how such a society reached its current state! That is not limited to political governance but present in every field of life. We need to analyse the problems more critically to find out suitable solutions.

It will be pertinent to understand how Indian society evolved. It is a largely accepted fact that general people from southern India are less corrupt. It coincides with the fact that north India had to face repeated foreign invasions, mainly from Muslim invaders who had very different social, religious, ethical and legal concepts as compared to the locals. South did not face that so often and so intensely. Those foreign invaders, first by the Middle Eastern or Central Asian Muslims and then Europeans (mainly the British) imposed a drastic change on our ways of lives. Many people, mainly men, used so many excuses to hide our own inability to protect our culture, our women, our ways of lives. Many such excuses took shape in form of religious dictates, distorted version of "tradition" and more awfully in the name of peace. Spread of “pardha” among women (which was present only among very few warrior communities like Rajputs, before Muslim invasion), imposing all sorts of rules (in the name of religion and tradition) to deter people asking questions, to curb personal freedom and our senses of justice; in short- to destroy of our own value and education system. Remember Nalanda university, one of the first and great organised universities in the world? It was destroyed by Bakhtiyar Khalji around 1200 AD, signifying the start of decline of Indian education and society.

It also changed our perception about corruption. We all witnessed that ruling class do not obey laws that are imposed on others. Different set of rules are applicable to different people, depending on caste, religion, closeness to ruling class and so on. Since then breaking laws was (and still is) equated to power and a sure sign of the socio-political elites. When a common Indian breaks a law or manage any special privilege, s/he feels proud and get satisfaction (may be temporary) to be equated as an “elite”. General Indians forgot that laws are for them, to keep them safe and disciplined. Agreeability and sycophancy, instead of critical thinking and logic, became the rule to climb both social and professional hierarchy. That practice gradually eroded the social shame factor, the best and most effective deterrent against corruption in any country, in any society. We started accepting corruption in the name of reality. Gradually we lost the sense of justice and honesty. University professors, scientists, doctors, bureaucrats, teachers, police and many others from India, in India or abroad (with or without foreign degrees) are as corrupt and dishonest as any illiterate person. It affected our ability to make or reform laws in post-1947 India. Still more than half of our current Indian laws (both civil and criminal) were introduced by our colonial British rulers to rule, not to "govern", their “native” subjects. Most of these laws are highly ineffective today. Some are even anti-national. Recent prosecution of noted social activist and reformer Dr Binayak Sen under British introduced sedation law is one such example.

Not many policy decisions in India are well planned. Not even the much hyped economic liberalization in 1991. That was a mere compulsion after mortgaging 67 tons of gold in the Bank of England due to years of misrule and closed economy. We were desperate to save our economy from total melt down. We could not reform our civil governance and judiciary to match the requirement of a free market, liberalized economy. We naively wished that everything will fall in place due to so-called open market economy and privatization. We conveniently forgot that true “open market” (even in US) is as utopian as communism. Greed of a very small section of our population increased exponentially but we could not protect majority others, the common man (“amm admi” as per popular politicking) from the greed that allowed massive, extra-constitutional manipulation of the system. Those social “elites” include not only businessmen and industrialists but also politicians, bureaucrats, corporate managers, scientists, professors, doctors and other professionals. It simply added to the already high level of corruption (due to socialistic quota-license raj regime of pre-1991 era). Magnitude of recent scams are good indicators. 

We practically ruined almost all (if not all) of our democratic institutions. Universities and institutes start resembling party offices. Internal control mechanisms were effectively destroyed. That’s why none of the recent high profile scams were detected and/or prevented by the internal control mechanism of respective departments or ministries. All the scams came to light due to outside private (by people like Subramanium Swamy) or 24x7 media or Supreme Court interventions. Not a single high profile current office bearers could gather the courage or honesty or both to support the services by people like Binayak Sen or the ongoing anti-corruption movement initiated by Anna Hazare, a class 7 educated gentleman (in real sense of the word). It says a volume about our current society. Our political masters initially gave in to the demands of Anna Hazare in the wake of many state assembly elections. Once the elections were over and government started negotiating with team Anna, the real intension of our “elected representatives” started becoming clearer. They were more interested to discredit team Anna or “civil society” or anyone who raises voice against all pervasive corruption, than any meaningful discussion to draft an effective Jan Lokpal bill. Does it take much intelligence to imagine the level of cooperation and desire of our elected representatives to pass an effective Lokpal bill in a parliament where about one forth of the members (154 to be precise) and 10 cabinet ministers are having criminal cases pending against them (civil litigation that include financial crimes are not included)? It partly explains why the government drafted, much less stringent Lokpal bill failed to pass in Indian parliament in last 42 odd years.

In India, collective decision making hardly exists. That trend is also evident among many Indian professionals, managing a group of people under them, in India and abroad. Most of the meetings or negotiations are used mainly to inform (rather than discussing) others what few people, so-called higher authority (or "high command") already decided. Feudal nature of decision making, lack of taking responsibility is rampant in every section of our society, starting from the highest level of government to private companies to the lowest level of family issues. Remuneration and/or promotion is not always based on performance but one's ability to please higher authority. Many times the credit for a good job and blame/responsibility for a sloppy work goes, rather imposed, on other people (not the person who actually deserve it). We generally try to gloss over any past mistakes, avoid fixing responsibilities and forget to learn from that. We prefer to "move on" and end up doing the same mistakes, again and again. We build new universities, institutions to improve quality (of research and higher education) or crate new ministries to improve governance without analyzing and learning why our old institutions or ministries failed. That ultimately give rise to the "chalta hai" mentality, tendency of shifting responsibilities, as we often witness among Indian professionals (both in government and private enterprises), in India and abroad. We probably can not afford to care how to build a motivated group.
   
That attitude helps spreading the culture of mediocrity, erode our productivity and quality of work in the long run, in every field of life, starting from research to business to civil governance. "Success" in such situations depends more on one's ability to use the existing corrupt practices and loopholes (of our system) than on taking responsibility, improve productivity, adhere to professional ethics and, more importantly, desire to change the system that can enable us to do better, enable us to dream to become the best.

That systemic failure makes many able people frustrated who ultimately become aloof. Provokes many to seek justice or other avenues to address personal grievances. This is one of the major factors for not only fast spread of extremist movements like naxals but also for huge brain-drain and very low quality reverse brain-drain or "brain-gain" as some call it (going back to India). Many of our better quality manpower, established abroad, prefer not coming back and settling in India. Some do prefer contributing from abroad. That allows them to speak the truth while insulating themselves and their families from retaliation, as we often see against people like Satyendra Dubey.

Our political parties are no exception. Not a single political party has internal democracy to attract, groom and promote people with true leadership quality. All are run like dynasties, feudal kingdoms (barring the communists, so far). That’s one of the reasons for increasing tendencies of common people to take laws into their own hands. If an able person is discriminated against and can pinpoint the responsible person or authority, it is almost impossible to gag or stop him to seek "justice". Such people eventually find their ways. That may or may not be so constitutional, neither do they care.

Many feel that India probably need or will soon have an Egypt-Tunisia type revolution. They probably do not understand that Indian corruption has a democratic twist, unlike Arab countries. It is true that there is a strong selection pressure to promote people without any sense of justice, honesty and courage (to speak out and remain honest). But if you have the required qualifications, you can join the select club to enjoy the fruits of corruption and lawlessness. That extra-constitutional rights are not limited to friends and relatives of the king or social “elites”, unlike Arab countries. That safety-valve eases a lot of pressure from the cooker and prevents it from bursting early. That’s why rise of common-man politicians like Laloo, Mulayam, Mayawati did not have much positive impact on Indian society, despite of a huge initial promise, so far social equality, corruption in public lives and transparency in governance is concerned.

We also need to understand that staging a revolution is not the same or end of reforming a society. In fact, that is just the beginning of a multi-act drama. Later stages are more difficult and need much longer term, more intense preparation. We need to figure out whom do we think would fill the gap, in case of a successful revolution, as many hopes for. We do not have enough, qualified and, most importantly, honest people to replace the existing lot. That vacuum is not limited to politics but present in every field, every occupation in India. Our "test score" culture kills both natural leadership quality and scientific/technical ability. Over-emphasis on database type information, occasional fascination with knowledge do not allow us to become “wise”. We pathetically lack the ability to ask questions, solve problems and generate novel ideas- be it technical or scientific or social issues like corruption. In short, all of our professionals (be it politicians, police, scientists, professors, lawyers, doctors, engineers and so on) are coming from the same society, from the same pool of people with almost same education and grooming. We must not expect to make any sustainable change with such bunch of (mostly) mediocre and corrupt people. Our task becomes harder considering the fact that not a single country in the whole world with considerable period of foreign rule ever became a developed country, so far.

What is the way forward? Or should we keep on marching the same path and expect a divine miracle to become a “superpower”, “developed” country in future, as many Indians dream against all realistic logic?

I think the solution lies within. We cannot expect everyone to become honest but ourselves. Majority of us support corruption (in the name of "reality") when it benefits us. We start shouting only when we are at the receiving end. We fool ourselves. We must understand that we can not eat the cake and have it at the same time. Our homes are the best place to start that crusade, if I may say so. We need to teach our kids to have some sense of justice and honesty. We must allow or force them to face consequences of their actions, from very childhood. At the same time, we must not force them to accept corruption in the name of "reality" or "practical sense". That is more important than some rote memorization and test-score based “education”.

I do acknowledge that its not only very hard but also dangerous to oppose corruption in Indian situation. Many of the time the official complain goes to the same person against whom you are complaining! This is systemic. That's why the rate of prosecution by India's "premier investigation agency", CBI, is so poor (particularly against influential politicians and bureaucrats); that's why so many politicians are opposed to include Prime Minister under Jan Lokpal bill (as proposed by team Anna). We need to be little careful here while speaking out against corruption. Sometimes we may have to become “anonymous” to voice our concerns in more formal settings, in offices, in societies and so on. That is doable in this age of internet and 24x7 media activity.

Lastly, we must bring back the social shame factor, the best and most effective deterrent against corruption. It is our responsibility to make those openly or known corrupt people feel ashamed and socially outcast. If we have the desire, we surely can avoid making any matrimonial relationship with a known, unacceptably high (relatively speaking) corrupt person or children of such people. Generally a tamarind tree does not produce mangoes.

Again, we need to remember that social shame is the best deterrent to minimize corruption in any society and very effectively used in western societies. Can we do that to start our dream of a better India, while joining rallies and praising people like Anna Hazare in public forums?


Short link-  http://goo.gl/Ur41P

Friday, January 28, 2011

"but, what can I do?"

"But, what can I do?" I hear that exclamation (or should I say "helplessness") quite often whenever people discuss democracy, civil liberty, corruption type issues in the context of India. I also used to belong to that category just few years ago and used to wonder "but, what can I do"! We used to feel so helpless. Immenseness of the problem make it more confusing. Where to start? It is truly overwhelming.

Now I am changing the gear a bit. Today I attended a very informative "public hearing" organized by "We the people" forum of the "Ohio Center for Law Related Education" (OCLRE). It was a state level competition among high school students to make them aware of their "right and responsibilities" under American constitution. Those students need to understand different laws and more importantly its interpretation. They get few months time to prepare for that, with the help of school teacher(s). Then they appear before a panel of jury, generally formed by different people from different walks of life- teachers, administrators, lawyers, judges and law makers (senators and congressmen; i.e MP, MLA equivalent in India). It is about 20 mins hearing time for each school. The students get 10 mins time for inaugural speech. Then the juries ask questions to determine how well they have understood the issue and and not jut parroting some data or prepared statement. Most of the time there is no "right" or "wrong" answer. Whatever the students say need to be clarified with logic and examples. One example- "do you support civil disobedience in a democracy and why". Students also get chance to freely interact with elected public representatives, lawyers, judges and so on. I like the idea. I wish we had something like that in our schools to know more about our country and, most importantly, its constitutional foundation. 

Now changing the gear again. I have a friend who recently went through a messy divorce. He got married to a lady from a rich family. The marriage did not click. They were not compatible to each other. It is not the fault of the man or the woman but their upbringing, core values as a human being were totally different. They spent seven days together after marriage. My friend went back to US to join his job while his wife remained in India. Despite of my friend's best efforts his newly married wife did not come to US. Finally he went back to India to attend his father for his deteriorating health. During his stay there my friend and his sister were arrested by police on charges of "demanding dowry, physical abuse and mental torture". It was very sudden development for him. Police arrested them during 10.30 at night. We need to keep in mind that his wife did not stay with her in-laws but lived with her own family for the whole time my friend was in US. My friend was a well-aware (at least he used to think so), "educated" person. He described his first feelings during arrrest was "helpless, scared to the death" in the police station. His passport was confiscated. The next day of his arrest, his father died but he could not go to see his dead father for the last time. They had no idea, whatsoever, about how the police work, how to handle them, what are his/his sister's legal rights, so on and so forth. They learned many things later; e.g legally police cannot arrest any women after 6.30 pm, both the police officer and the person need to sign (or thumb impression) the arrest warrant when police is arresting a person and many such laws, norms, legal ways to fight back against police atrocities and general corruption. 

During the whole divorce battle, they learned how our laws are twisted, sold and misused by almost everyone, starting from police, lawyers, judges, media and so on. Everyone was asking for bribe from them. Even court judges were no exception. The dowry related law is very clear to mention that both parties, who give and who receive dowry should be prosecuted. But there is not a single instance that any parent who claim to have given dowry had ever been prosecuted in Indian legal history. If the marriage is successful the money or items given to the groom becomes "gift" while the same becomes "dowry" if the marriage goes bad! My friend learned that despite of giving ample evidences that police were not following laws and harassing them was not sufficient for our judiciary to protect the victims. they learned that police can arrest anyone without showing arrest warrant, police can drag any woman to the police station at night 10.30 pm (the whole drama in police station went on till 2.30 am), police can file a FIR against my friend and his family claiming him (and his family members) to beat the bride when the lady was not even in their house and my friend was in US. In short, my friend came to realize, for the first time in his life, that it is totally different to write laws in a book (called constitution) and practicing that in real life.

The only good thing my friend did was to refuse to bribe anyone. The family members of the bride asked 25 lakhs rupees for an out-of-court settlement. My friend had no clue why he need to pay anyone when he did not take any dowry, never even shouted at his wife. He continued to tell his in-laws to punish him if they can prove a single crime alleged against him. After all, "they should seek justice to protect the dignity and the rights of their own daughter, and that should be more important than 25 lakhs rupees"! 

He was also worried that if he can manage that huge sum of money (which he never had) and give that to the lady's family (and police, judges etc.), he practically accepting all their false allegations. That's the main reason he refused to bribe anyone or indulge in any monetary transaction to settle it out-of-court. To cut the long story short, he ultimately won the legal battle after a long fight.

Now my friend knows India better. His sister left her PhD from New York University. Went back to India and started her own fight as a social activist. They became aware how helpless few remaining honest government and other police officials are, who tried their best to get justice for them. They merely could save my friend form more legal and other harassments; but still could not punish any of those corrupt government officials or punish the family members of the lady who brought false allegations against my friend and his family. 

I told this story not to highlight the fight of my friend but to show how ineffective our education system is, to groom our future citizens. Mugging up some numeric table or laws of motion is not that important than to know the reality, to know our system, to know what options we might have if we face same situation, if we want to remain honest and deal the system to deliver justice. We accept corruption in the name of reality. We make our ways through it- bribing different people and bullying weaker ones. We naively wonder why so much black money around, why we can never minimize corruption in public lives that is ruing our country from its core. And then wonder, "but what can I do?"

Would it not be a useful idea to take our primary and high school students to local police stations, court houses and let them witness a trial? Or have a guided tour to our state and national parliament houses, meet law makers whose actions practically control our daily lives? Our future citizens need to know how police work, how government officials deal with fellow citizens, or even to those who has committed a crime or alleged to have committed a crime. They need to know how to make laws, what social and ethical issues they need to deal with as a politician or a judge or even a common citizen. I think, they need to know the constrains our police, judiciary and political system. We owe it to them to prepare themselves for the eminent and upcoming future they have to handle and take responsibility of. 

I know many parents will be shocked to know that the school is planning to visit the local police station or a court house with their beloved children. We, the adults, try our best to stay clear from such places, for reasons we all know. Probably police personnel will not like that idea either to expose themselves in front of some kids, which may have their own children. But just think a little deeper. It will not only expose our future citizens to know the reality and get enough time to prepare themselves to handle it, whatever it is- good or bad. If some of them are not satisfied, they may try to come up with a solution to change it in future. Police and law makers will (eventually) find it little embarrassing to tell lies to these little kids who may confront them, if caught. Older, more "practical" people might find it hard and/or even risky to ask the same questions they should have asked to our mighty policy makers, police and civil administration.

Here in western societies people say, "if you do not like any politician, then try to become one". In India, we never groom ourselves, our kids to become a true leader, a true politician. Not a single political party in India have any democracy in electing their own leaders, about deciding any policy within the party. That is one of the reasons why we get that type of politicians and policies we have now. There is almost no chance to get our own Barak Obama, from any party in India. We rightly get what we deserve. We wrongly think that by insulating our kids from reality we are protecting them. In reality, we are making them incompetent to have a functional democracy, to take responsibility of their own lives and country and more importantly we force majority of them to stand in the already long que in front of many foreign embassies. 

Forcing the kids to go to private tuition or judo or cricket or tennis or computer class probably is important. But I will ask teachers and parents to think about what they can really do, in real life, to make a positive and sustainable change in attitude as a personal attempt to make a brighter future for themselves, for their own children and the country. 

This is one of the things that you can do, I can do, we all can do as individuals. Worth a try, I think.

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Friday, December 03, 2010

The Great Dilemma of the Life Sciences



It is an excerpt from the chapter, "The Great Dilema of The Life Sciences", in the book, "Heraclitean Fire: Sketches from a Life Before Nature" by famous biologist, Erwin Chargaff. The book was published in 1978 by Rockefeller University Press, New York. Hope you will enjoy reading it, in the context of today's research scenario. I enjoyed reading it and feel like sharing with others. 

One man or two may decide to study a certain beetle. Whether they do this because the animal is pest or biological delight is immaterial. If they find something of scientific interest, there will soon be ten others and more who will do the same. Once there are a hundred men studying the beetle, they will form a society and publish a journal. A society creates a profession, and a profession cannot be permitted to die. It is upto the nation to support it. If the nation can be persuaded, there will soon be a thousand members of the society for the study of the beetle. It is obvious at this stage the beetle can no longer become extinct, for what would all these experts do who may well outnumber the beetle? Then a foundation will arise whose lay members- influential bankers, society ladies- will neither know nor care whether their function is to help with the eradication or preservation of the beetle. They know one thing: they must support those who study the beetle. There may even be a Beetle Ball.

Professional scientists have, by necessity, limited vision. I always tried not to be professional scientist, since I dislike professional professionals. What I used to call "human beings" are becoming rarer as I look around. Not so long ago, St. Augustine would say: "the heart speaks to the heart". But now computer talks to computer. Most people I meet in my or other universities seem to be rejects of IBM. They are really the narrowest, the dullest kinds of experts or specialists; they are essentially molecular podiatrists: people who know all about the fifteenth foot of the centipede.

When you spend your life watching a bubble chamber or running cesium chloride gradient, you may become an expert bubbler or gradient runner, but there is little likelihood of your thus acquiring much wisdom. There is, in fact, a good chance that such people will turn into a very dull fellow indeed, wasting their lives by trying to outrun ten other dull fellows with whom they are in competition.

How is science done in our days? Here I must immediately make a distinction between science as a profession and science as the expression of some of the faculties of the human mind. The two are not necessarily connected. When someone tells me "I am a professional scientist," it does not automatically mean that he is a scientist. The distinction I am suggesting here has nothing to do directly with the question of talent. There have always been more or less gifted scientists, and there were even a few, very few, scientific geniuses. But what I want to bring out is that as a profession science is one of the most recent ones. It barely existed when I began my studies. Perhaps the exception is chemistry, where, when you called yourself a professional chemist, people would assume that you worked in the chemical industry. This was about the only mass outlet for academically trained scientists. It was not an accident that, when the science departments of the universities began to swell and to expand, it was always the chemistry department that led the way; just as the first modern teaching and research laboratory at a university was Liebig's chemistry laboratory in Giessen.

Otherwise, one entered a career in science, just as in history or philosophy, by trying to become a teacher at a college or even a high school. There were very few jobs, and almost none that paid enough to live on, except for the position of the professor himself. And there was usually only one professor for a discipline. Hence the old students' saying that there were only two ways to make a university career: per anum or per vaginam. You tried to become the professor's darling or you married his daughter. Obviously, this limited the choice: some professors were very nasty, some daughters were very ugly. Girl students were altogether out of luck, but there were only a few of them.

You may conclude - and you are right - that this was a most unpleasant system. But it had one advantage: it acted as a sieve, letting through the few who could not do otherwise. By requiring what amounted to a pledge to poverty, it kept out all those who, to use a nasty term, were not "highly motivated." It produced a slightly smaller number, but probably a much higher density, of good scientists than does the present system.

I should by no means wish to give the impression that I am in favor of the old system. It was abominable. Nor am I, on the other hand, in agreement with the way things are done now; for I am convinced that with our methods of organizing and supporting it we are effectively killing science. We are destroying the whole concept of science, as it had developed over the centuries.

This may sound to you awfully apocalyptic, and I ought to clarify it a little. I shall try to do this under four headings: What has science done to the universities? What have the universities done to science? What has science done to the country? What has the country done to science?

All these interactions have to do with science as a profession. But you will remember that I have made a distinction between this aspect and that of science as a product of the human mind. In this respect - namely, as the search for truth about nature - science began as a branch of philosophy, and for me this connection has never broken off. Science is an admirable product of human reasoning, as admirable and astonishing as are music or poetry or the arts. Previous generations understood this very well. For instance, I am a member of the American Academy of Arts and Sciences and, until recently, before Columbia sent me down for recycling, I belonged to their Graduate Faculty of Arts and Sciences.

As a mental occupation, as a product of the human mind, science does not operate on a time scale. Just as nobody could have told Mozart how many operas he ought to write, there can be no five-year plan for science. It comes as it comes, it goes as it goes. Should all melting points be raised by 10 percent; are six laws of thermodynamics better than three? But when America decided to go into science in a big way - and this really took place only within the last thirty or forty years - it went into it in a crazy fashion. This country has always had the tendency to blow up every balloon until it bursts, and it has done it also with science.

What science has done to the universities is that it has inflated and disfigured them; it has left them more bankrupt than they were before. The large private universities have been turned into huge corporations whose only business is to lose money. There are exceptions, but, in general, power-hungry, empty-headed money grabbers have taken over. The true and only function of a university, namely, to help young people find themselves by bringing to them the accumulated memory of mankind, has been swept aside. By misunderstanding, through overemphasis, of the old adage of the unity of research and learning, research has been made into a teaching tool, into a most expensive and stultifying one, forcing every student to become a researcher and trivializing the purpose of scientific research. Thousands of meaningless and costly experiments are performed to persuade the young that water boils at 100 degrees (Celcius). We are now paying the price for excessive veneration of the value of inductive reasoning.

Now to my second question: What have the universities done to science? They have bled it for overhead; they have cheapened and vulgarized it to the point of nonrecognition; they have made it into a public-relations "gimmick." If the products of this kind of education often still are so good, it testifies only to the resilience of young minds. But many are damaged irreversibly.

What has science done to the country? Obviously, a lot of good and a lot of evil. If the republic envisioned by Plato had come to pass, that is, a dictatorship of wise philosophers, may be no evil would have come to the state from science. But how many wise men will you meet in your future long lives? When I look at our leading statesmen, there are brought back to me the immortal words that the Duke of Wellington once spoke of his generals. "They may not frighten the enemy, but, by God, they frighten me!" The thoughtless, almost automatic use of science as the seed of technology has landed us in a fearful mess. The cry that what we need is more and ever more science has lost all persuasion, as far as I am concerned. The republic will not be saved by geese, not even by geese with a PhD.

What has the country done to science? In a way, I have already answered the question. When you have been a scientist all your life, going to the laboratory every day and spending all your days among other scientists, it becomes hard to imagine that there still are people in this country other than scientists, although an optimistic forecast made a few years ago promised me that in less than hundred years there would be more scientists than people in the United States. In any event, as I have already mentioned, the country at large views science with great diffidence and often with dislike; and the rain of suspicion falls alike on the guilty and on the just. I don't want to go into the tedious arguments about pollution and DDT and all the rest. I shall also not discuss whether ten million blackbirds ought to have been killed, by Tergitol or otherwise; nor shall I have anything to say about Napalm, that innocent pastime of a Harvard professor.

Our kind of science has become so dependent on public support that nobody seems to be able to do any research without a handout. If their applications are turned down, even the youngest and most vigorous assistant professors stop all work and spend the rest of their miserable days writing more applications. This continual turning off and on of the financial faucets produces Pavlovian effects and a general neurasthenia that are bound to damage science irreversibly. It would have been much better if it had never got so rich before getting so poor, for in the meantime many young people have been lured into a career that may never materialize.

P.S. Not much has changed- probably gone worse ever since.

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Sunday, October 24, 2010

Steady-state economy and de-growth models of development.













Since last few years I was wondering how many people this world can sustain. Obviously the answer depends on how we define sustainability and what quality of life we like to have to calculate that number. Initially we used to think that this world can sustain 4 billion people. Later we revised that data to 6 billion. Now we know that world can (rather “have to”) support more than that. One report suggests that we already need 1.2 earth to sustain just our current population (1). 


Now think that majority of world population (including those in rapidly developing countries like India, China, Brazil etc are nowhere near the desired living standard that people in very few affluent, first world countries enjoy. The same question is intimately related to many other questions related to 'sustainability' and 'growth', two favorite terms for many, if not majority, corporate, government and even non-profit organizations worldwide. These terms are highly misused or used very vaguely as an advertising tool.


I was also wondering what type of model of development we should have, to sustain this world and our quality of life. It becomes more important for developing countries like India where we almost constantly hear about "development" and conflicts arising from that. In one hand, we hear the conservation and global warming experts and enthusiasts like Al Gore who tell us to consume less, create less carbon footprints in our daily lives. On the other hand, we are constantly hearing many economists and policy makers that we need “growth”, that we need to spend more (i.e consume more). National governments, corporate houses, even NGOs; all are talking about this "growth". From our childhood we had an impression that low or zero “growth” is very bad! I was confused like many other general citizens, who want to behave responsibly. Then I came across an interesting article in a reputed research journal, “EMBO Reports” (Sep 2010 issue, Vol. 11, No. 9, pp. 659-663) (2). Basically the article is about consequences and desirability of a second green revolution to feed ever increasing global population (and eventually turning the world into a giant farmhouse).

The article emphasizes on alternative economic models that recognize ecological limits of human development and emphasize social equality. It described two alternative economic models. The first one proposes a steady-state economy: one that has stopped growing in terms of GDP, but continues to improve quality of life and is maintained by an ecologically sustainable rate of resource throughput and a constant human population. The second one is a sustainable de-growth model that has been defined as “an equitable down-scaling of production and consumption that increases human well-being and enhances ecological conditions at the local and global level, in the short and long term”. The paradigm is that human progress without economic growth is possible. It has been shown repeatedly that GDP per capita does not correlate with overall happiness above a certain level of satisfying people’s basic needs. According to a recent article, earning more than a threshold level does not translate into increasing overall happiness and satisfaction of life, while may have negative impact on quality of life. That cut-off value is ~ $ 75,000 per annum per family in USA (as of 2010) (3).

The defenders of de-growth emphasize that this process is “not the same as recession or depression— there should be no social or quality of life deterioration—nor does it promote a return to a fictitious pre-industrial pastoral past”. 

It is almost impossible to tame greed of people (for both power and money), mainly the ambitious and intelligent ones that influence public policies and run private industries through the way current “growth” based economic model is practiced. That's one of the reasons why many, including national governments, prefer GDP type macro-economic parameters despite loud demands to adondon GDP as the overriding measure to indicate social and economical development (4). In 1972, the tiny Himalayan nation of Bhutan opted to base its policy-making on indicators of 'gross national happiness', with King Jigme Singye Wangchuck declaring that this measure was more important than more conventional indicators such as gross domestic product (GDP). Today, after three decades and the biggest financial crisis since the Great Depression, his remarks seem prescient. A consensus among economists and policy-makers is growing that governments' reliance on GDP as the main proxy for social well-being and progress is leading the world in wrong and unsustainable directions (5).

It raises a serious question that if I have talent and ambition, how much right (both ethical and legal) do I have to get what I want! How beneficial or harmful is the typical “winners take it all” mentality for overall development of any society? Let me re-phrase the question. If powerful countries have the economical, technological and military might, does that give it the right to mow down other countries that does not agree with it OR for expanding its economic and/or political strength at the cost of many other people around the world? And more importantly, how will that affect our own social and economic prosperity? 

Anyone can extend the logic at any level- starting from within a family, or an organization, or a city, or a state or a country.

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Tuesday, December 29, 2009

We can do something does not mean we have to do that


I was watching the sixth sense technology lecture by Pranav Mistry in TED India forum. No doubt it is a nice idea and I appreciate that. I was checking the comments, and, as expected too many people are excited.


I was dreaming a little further. Suppose I can implant a microprocessor in one’s brain (that can communicate with his own senses), attach that with a broadband network and then enable the person to communicate with the world without any more external device, at any time, day or night. He can get any data, any picture or just anything available in the web. He will be able to store huge information there in his head and never forget anything. If I am successful in doing that and give a lecture on TED forum, I think I will get huge “congratulations” for “extraordinary innovation”, making many Indians “proud” and so on. But, please think little deeper. Do we need such a (bionic) person in the first place? Will that (bionic) person be a better human being, more genius in inventing or innovating? Will it be worth doing so? Should there any of that kind of technology be invented or be allowed? Answer for any of those questions is a big no for me. It seems that it’s almost impossible to make many people understand that we can do something does not mean that we have to do that.
We have enough technology, sufficient medical and agricultural know-how to make this world a much, much better place. Judicious use of already existing technology, proper application of our current knowledge can make a great difference. In fact, when industrial revolution started in Britain a couple of centuries ago, it promised “eradication of poverty and a more just society”. We all now know that industrialization made things worse. Agrarian societies are fairer, distribution of wealth was more equal. Please do not misunderstand me. I am not suggesting going back in time to have an agrarian society.



Most of the time, when we get any new idea, we become so excited that we tend to lose sight of bigger picture. We tend to justify the means than the goal. I know that we probably can not and should not stop innovations; but, I think, it will be better not to lose sight of the bigger picture.

Short URL: http://goo.gl/4l3pqq

Tuesday, September 08, 2009

How important money is to decide which profession to join?

Last few years Indian higher education and research sector is loudly asking for more salary and other financial benefits. Majority of them argue that higher salary will attract better talents, help improving the rapidly falling quality of Indian higher education and research.

I have a serious problem with the idea that increase in salary and other monetary benefits will increase quality while it definitely attract many un-worthy candidates into that area. If survival and progress of a person in a specific area is not dependent on actual productivity and accountability, then any increase in monetary benefit will do more harm than good.

Currently higher education and research in India is nothing but a tool to address huge unemployment problem without any accountability towards the nation or the subject.

If you do not love a subject but join it simply because of money, then there is a very high chance that you are just mediocre. Your main strategy to survive will be to belong to like minded mediocre people and form a group. Then wipe out any potential trouble maker- in form of genuine talented colleague or a student/junior who reminds you of your mediocrity. The only motivation for such people, in any profession, is money. It’s not very surprising that the main topic of discussion in majority of Indian universities and institutes is salary hike, pay commission, increase in TA-DA, HRA and so on. Very rarely we can hear any scientific discussion. This is not limited to science/research but almost any field of life there. We generally forget that India has substantially increased its higher education and research budget, both in terms of total money and percentage of GDP, since independence. Many new universities and institutes are coming up on a regular basis. Yet published reports show that we going downhill, so far quality is concerned.

Let's check one specific example of highly hyped IT sector in India. Despite of being one of the most prosperous industries, innovation-invention is almost zero. Not a single core software (operating system, JAVA, C++, Oracle etc) is developed by these rich Indian IT companies, using Indian IT professionals. We are happy to apply existing technology to solve customer specific problems and to do routine, maintenance jobs. Why so? Now analyze who is joining IT and why? Any Tom-Dick-Harry can become an “IT professional” who have passed bachelors degree with some math (not always necessary). Few months training will be sufficient to give him/her the job of an “IT professional” that will pay more than a teacher in a collage. On top of that, possibility of lucrative foreign tour/postings (again, mainly for money) provokes many to join IT. In this overwhelmingly majority of mediocrity, original talents in IT are lost. Many great talents in other fields are also lost in this IT-mania. This is one of the reasons why we will never have our own Bill Gates in IT or Obama in Indian politics in near future.

Thankfully, there is no software or fixed rule to generate talents and promote out-of-box thinking. You need to provide suitable environment to groom talented people. Money is needed but if money becomes the sole parameter to decide which profession to join, then all the professions and overall quality of life in that society gets affected. The same is true for almost any profession in India, starting from IAS-IPS (civil servants), to IIT, to IT, to biotech. No amount of screening, no amount of stringency during entrance exams can prevent that. We all know how rigorous UPSC selection process is, yet Indian bureaucracy is the worst in Asia (1). our IT is capable to do routine maintenance jobs, our biotech research is good for imitating western research and technology and/or BPO jobs. Many of these professions are well paid; many of these industries have good financial muscle but still lack originality, still lack efficiency and severely lack accountability towards the profession and towards the society.

I think that there should be legally binding cap (for salaries and executive benefits) for all the top executives of big industries (say, with more than 1 billion USD turn over). I am sure that it will not cause any serious attrition of talents. Talented people will continue to enjoy their professions as before. But such cap will help distributing the money to novel R&D projects, to other junior staff to make their lives little better (to reduce job loss and salary erosion, mainly during recession time like this). Focus on short term gain and over crowding of mediocre people (who joined the job only for money in many financial institutions and banks) are some of the important reasons for our current problem in global economy.

Lately I came across this excellent presentation. It may help you understanding why higher remuneration improves performance only for mechanical or routine jobs while reduce performance when, even, rudimentary cognitive skill is needed. It suggest, "just offer a minimum but enough salary and then take money out of the equation to improve both motivation and performance".

Real talents, the dedicated ones, join a profession they love. Money is important but must not be the main parameter, mainly in creative professions like research. Creative ego, professional success and institutional power (fame) are the most important driving forces for talented people. If someone joins a profession for money and the only day s/he looks forward to go to the office is the salary day then s/he should understand that there is a severe problem.

Short URL: http://goo.gl/LM9Q0y